Research Area: Joint Health
8 ingredients studied for effects on Joint Health — sorted by research relevance.
Vitamin C (Ascorbic Acid)
Vitamin C is essential for collagen synthesis and other normal body functions, with approved EFSA claims. Megadoses show no clear benefit beyond adequate intake.
Vitamin D3 + K2
Low vitamin D levels are common in northern climates. Supplementation is comparatively well studied in deficiency; K2 is often combined but has weaker standalone evidence.
Silicium
Silicon is marketed for skin, hair, nails and connective tissue. Biologically plausible but clinical evidence is limited.
Kollagen
Collagen is one of the most popular supplements. Human trials support benefits for skin elasticity and joint markers; broader anti-aging claims remain unproven.
Glucosamin
Glucosamine is a classic joint supplement with mixed evidence. Some data supports potential benefits, but not enough to warrant broad therapeutic claims.
Curcumin (Turmeric Extract)
Curcumin modulates inflammatory and oxidative pathways; moderate effects on CRP, IL-6, and joint pain—but only with enhanced formulations. Bioavailability is the limiting factor.
Hyaluronsäure
Endogenous glycosaminoglycan with high water-binding capacity. Multiple RCTs demonstrate moderate effects on skin hydration and wrinkle reduction; oral joint data weaker.
MSM
MSM is marketed mainly for joint health and inflammation. The data aren't empty, but significantly smaller than most claims suggest.