Research Area: Schmerz
4 ingredients studied for effects on Schmerz — sorted by research relevance.
Moderate Evidence
Curcumin (Turmeric Extract)
Curcumin modulates inflammatory and oxidative pathways; moderate effects on CRP, IL-6, and joint pain—but only with enhanced formulations. Bioavailability is the limiting factor.
Likely safe
Strong Evidence
Omega-3 (EPA + DHA)
Omega-3 fatty acids (EPA + DHA) are among the most thoroughly studied supplements. Evidence is strong for triglycerides and high-risk cardiovascular patients; smaller for healthy individuals.
Safe EFSA ✓
Strong Evidence
Magnesium
Magnesium is involved in over 300 enzymatic reactions. Low intake is common. The form significantly affects bioavailability and tolerability.
Safe EFSA ✓
Weak Evidence
D,L-Phenylalanine
DLPA combines the neurotransmitter precursor L-phenylalanine with the D-form, which may prolong endogenous endorphins. Moderate evidence, older study base.
Likely safe