Research Area: Blood Pressure
20 ingredients studied for effects on Blood Pressure — sorted by research relevance.
Quercetin
Quercetin is a plant flavonoid with antioxidant and senolytic potential. Human senolytic evidence is limited to tiny pilot studies using Dasatinib+Quercetin combined — not quercetin alone.
NAC (N-Acetylcysteine)
NAC is a glutathione precursor with established medical use. As a longevity supplement (especially as GlyNAC), early human data is promising but limited.
Taurin
Taurine is an amino acid with a central role in energy metabolism. Animal and observational data have sparked aging research interest; robust human evidence is far more limited.
Vitamin D3 + K2
Low vitamin D levels are common in northern climates. Supplementation is comparatively well studied in deficiency; K2 is often combined but has weaker standalone evidence.
EGCG (Grüntee-Extrakt)
EGCG is green tea's most abundant catechin, studied for metabolism and cellular protection. High-dose supplements carry documented liver toxicity risks.
Beta-Alanin
Beta-alanine elevates muscle carnosine and improves high-intensity exercise performance in 60–240-second efforts; it's a sports tool, not a longevity supplement.
NR (Nicotinamide Riboside)
Like NMN, NR is a NAD+ precursor — but unlike NMN, it is approved as a Novel Food in the EU. Human studies confirm NAD+ elevation; clinical benefits remain unclear.
Hydroxytyrosol
Hydroxytyrosol is an olive polyphenol studied for oxidative stress and vascular markers. One of the few EFSA-approved polyphenol claims.
L-Citrullin
L-citrulline may boost nitric oxide production and is linked in studies to improved blood flow and endurance performance during physical exertion.
Pterostilben
Pterostilbene is a resveratrol analogue from blueberries with superior bioavailability (~80% vs 20%). Similar mechanisms (SIRT1, AMPK) but fewer human studies to date.
Caffeine
The world's most widely consumed psychoactive substance. Hundreds of RCTs confirm effects on alertness, reaction time, endurance, and short-term cognition.
Kalium
Potassium is essential for blood pressure, nerves and muscles. Often more important via diet than supplementation—and potentially risky when overdosed.
Sulforaphan
Sulforaphan activates Nrf2-dependent defence mechanisms and is typically sourced from broccoli sprouts. Strong preclinical evidence; clinical data still building.
Resveratrol
Known for sirtuin activation in animal models. Poor oral bioavailability (<1% free form) translates poorly to humans; a 2026 umbrella review found no convincing metabolic effects even in diabetics.
Magnesium
Magnesium is involved in over 300 enzymatic reactions. Low intake is common. The form significantly affects bioavailability and tolerability.
L-Theanine
L-theanine promotes relaxed alertness via alpha-wave activation. Best evidence for caffeine synergy; moderate effects on stress markers. Alone, cognitive benefits are limited.
CoQ10 (Ubiquinol / Ubiquinone)
CoQ10 reduces mortality in heart failure (Q-SYMBIO); relieves statin-induced muscle pain. In healthy individuals without heart disease, benefits are unproven.
Myo-Inositol
Myo-inositol has solid RCT evidence for PCOS and insulin resistance. Promising but limited data for anxiety and panic disorder.
Cholin
Choline is essential for cell membranes, liver, and acetylcholine production. Important if underprovisioned—but not all choline forms deliver the same brain benefits.
L-Tyrosin
L-Tyrosin is an amino acid precursor of dopamine, noradrenaline, and adrenaline. Studies show cognitive benefits under acute stress and sleep deprivation.